One year later, I had a young bitch in for her last puppy shot. Within minutes of this shot, she begin breaking out into hives, and her skin turned bright red. She then starting going into anaphylactic shock. Without the quick actions of my vet, she would have been dead in minutes. When I questioned him about this, he stated that this does happen from 'time to time'. He suggested, and I agreed, that she should never have another shot in her life. Since that time, I have read everything I could find on this topic, and this article will address these findings.